Imaging pain in humans

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Imaging pain in humans.

Cerebral pain mechanisms are poorly understood when compared with the peripheral nervous system and spinal cord. Reasons for this have included a lack of suitable examination techniques, especially in humans. The recent availability of a number of relatively non-invasive methods that can produce images of functional brain activity has renewed interest in this field. Three of these techniques wi...

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Imaging CNS modulation of pain in humans.

Pain is a highly complex and subjective experience that is not linearly related to the nociceptive input. What is clear from anecdotal reports over the centuries and more recently from animal and human experimentation is that nociceptive information processing and consequent pain perception is subject to significant pro- and anti-nociceptive modulations. These modulations can be initiated refle...

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Imaging of acute versus pathological pain in humans.

Pain subserves different functions. Acute pain from the intact body alerts the victim to immediately react and withdraw from the bodily threat, ideally before an injury happens. However, during manifest injury and tissue inflammation, withdrawal and flight are no longer adaptive. Instead, sparing the affected body part to promote healing requires heightened awareness and avoidance behaviour ove...

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Imaging how attention modulates pain in humans using functional MRI.

Current clinical and experimental literature strongly supports the phenomenon of reduced pain perception whilst attention is distracted away from noxious stimuli. This study used functional MRI to elucidate the underlying neural systems and mechanisms involved. An analogue of the Stroop task, the counting Stroop, was used as a cognitive distraction task whilst subjects received intermittent pai...

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ژورنال

عنوان ژورنال: British Journal of Anaesthesia

سال: 1995

ISSN: 0007-0912

DOI: 10.1093/bja/75.2.209